EXOSMART®
Discover the future of regenerative therapy
exosmart® is a Class IIa medical device approved by Swissmedic. Thanks to its innovative selective ultrafiltration technology, it enables the efficient concentration of plasma or saline solutions and the production of a preparation highly enriched with autologous exosomes.
This innovation makes it possible to achieve a high concentration of autologous exosomes, reaching up to 30 trillion platelet-derived exosomes per ml.
Designed to collect and hyperconcentrate autologous exosomes obtained from peripheral blood, bone marrow concentrate, or adipose tissue, exosmart® opens new perspectives in the field of regenerative medicine by providing practitioners with a standardized, safe, and highly efficient solution.
Swissmedic Approved
Why EXOSMART®?
Precision. Purity. Performance.
exosmart® was engineered for the modern regenerative practice — combining scientific rigor with clinical efficiency to deliver a truly personalized patient experience.
100%
Autologous
Derived exclusively from the patient's own blood — no donor material, no allogeneic risk, no ethical ambiguity.
High
Concentration Yield
Advanced processing protocol delivers a highly concentrated exosome fraction optimized for clinical potency.
Streamlined
Workflow
designed for in-practice use — from blood draw to clinicalgrade exosome preparation with minimal chair time.
The Science
What Are Autologous Exosomes?
Exosomes are nanoscale extracellular vesicles, typically ranging from 30 to 150 nanometers in diameter. They are secreted by virtually all cell types and are abundantly present in peripheral blood. They act as true regulators of intercellular communication, carrying a complex cargo of proteins, lipids, messenger RNA, and microRNAs that directly influence the behavior of target cells.
In the field of tissue regeneration, exosomes coordinate essential biological processes such as the resolution of inflammation, cell proliferation, angiogenesis, and extracellular matrix remodeling. Their autologous origin ensures exceptional biocompatibility, eliminating the immunogenic risks associated with allogeneic or synthetic alternatives.
exosmart® concentrates the patient’s own exosome population for immediate clinical use, providing the body’s natural regenerative intelligence in an enhanced form.
Key Biological Properties
Intercellular Signaling
Carry bioactive molecules that modulate recipient cell gene expression
Tissue Regeneration
Stimulate repair cascades including proliferation, differentiation, angiogenesis
Immunomodulation
Autologous origin ensures zero immunogenic response and full biological compatibility
Dimensions and biological activity
Exosomes generally have a diameter between 30 and 150 nm. Despite their extremely small size, they represent major biological carriers involved in cellular communication and the coordination of tissue repair processes.
Clinical Applications
exosmart® supports a broad spectrum of regenerative and aesthetic indications, enabling clinicians to offer next-generation personalized treatments across their practice portfolio.
Skin Rejuvenation
Stimulate collagen synthesis, improve skin texture and tone, and address fine lines, laxity, and photoaging through targeted exosome delivery to the dermis.
Hair Restoration
Support follicular regeneration and scalp microenvironment remodeling for patients experiencing thinning, androgenetic alopecia, or post-procedural hair loss.
Regenerative Medicine
Integrate exosome therapy into broader regenerative protocols — supporting tissue repair, wound healing, and recovery optimization across orthopedic and systemic applications.
Aesthetic Procedures
Complement and enhance existing aesthetic treatments — from laser and microneedling to injectables — by amplifying the regenerative response and improving patient outcomes.
EXOSMART® Concept
During the centrifugation step of PRP or bone marrow concentrate, exosomes are released from cells and remain suspended in the plasma.
Exosomes are also released during the washing and microfragmentation steps of adipose tissue processing.
exosmart® is designed to process and ultrafilter the plasma or physiological solution contained in the collection bag, allowing the recovery of released exosomes as well as other biologically active components.
The technology is based on an ultrafiltration membrane with a molecular weight cut-off of approximately 15 kDa and an average perfusion pore diameter of less than 5 nm. Thanks to its selective concentration capacity, water and low molecular weight ions pass through the membrane, while exosomes, proteins, cytokines, and cells are retained and concentrated.
Under the pressure generated by the syringes, biological components flow through the hundreds of microcavities within the exosmart® system. At the end of the procedure, the concentrated exosomes, cells, and cytokines are fully recovered in the syringe.
The fundamental principle of exosmart® is the complete reinfusion of the patient’s own autologous cells, cytokines, and exosomes.
exosmart® can be used with:
- Blood plasma
- Blood serum
- Bone marrow
- Adipose tissue
Ultrafiltration technology
exosmart® was developed through the combination of a filtration technology based on capillary membranes and advanced blood product concentration techniques.
HIGHLY CONCENTRATED
Up to 30 trillion
platelet-derived exosomes per ml
Thanks to its selective concentration and ultrafiltration capacity, water and low-molecular-weight salt ions are removed into the collection bag, while exosomes, proteins, and cells are retained and collected within the system’s fibers.
Nanoporous fibers: filtration cut-off of approximately 15 kDa with an average perfusion pore diameter of less than 5 nm.
Protocol
How It Works
The exosmart® workflow is engineered to integrate seamlessly into your existing clinical environment. Three precise steps transform a standard venous blood draw into a potent, patient-specific exosome preparation — ready for immediate therapeutic application.
The entire process is designed to minimize procedural complexity while maximizing biological yield. exosmart® requires no specialized infrastructure beyond standard in-practice phlebotomy capabilities — making advanced autologous exosome therapy accessible to practices of all sizes.
Blood
Collection
Exosome
Generation
Clinical
Application
Why Partner with exosmart® ?
How It Works
exosmart® is currently available to qualified clinicians and aesthetic practices across Switzerland — the birthplace of precision medicine and a global center of biotechnology excellence.
Differentiate Your Practice
Offer a genuinely personalized regenerative therapy that no offthe-shelf product can replicate — built from each patient's own biology
Expand Your Protocol Portfolio
Complement and elevate existing treatments — from PRP to injectables — with a scientifically advanced autologous modality
Clinical & Commercial Support
Access dedicated training, clinical protocols, and ongoing scientific support from the exosmart® team
Built for Modern Practices
Fast workflow, minimal overhead, and a premium patient experience that reflects the caliber of your clinic
exosmart® is an autologous exosome technology. Available exclusively to qualified healthcare professionals. Intended for clinical and investigational use only in markets where its use is authorized. Please consult the applicable local regulations.
Bring Personalized Regenerative Medicine to Your Practice
Join a select group of clinicians redefining what is possible in aesthetic and regenerative medicine.